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PATIENTS with severe sepsis and multiorgan dysfunction syndrome often have development of abnormalities in brain function manifested as delirium, coma, or both.1–5 Delirium in intensive care unit (ICU) patients is a predictor of a threefold higher mortality over 6 months, higher cost of care, and significant ongoing cognitive impairment among survivors even after adjusting for severity of illness and other covariates.4,6–9 These social and economic costs associated with delirium highlight the need for strategies to prevent delirium by identifying modifiable risk factors.Although numerous risk factors for delirium have been identified, data from previously published non-ICU cohorts do not necessarily apply to the ICU.Anticoagulation ARDS Cardiac Arrest Cardiac Surgery Cardiology Christmas fun COPD Delirium EBM ECHO ECMO EGDT Fluid Head Injury Humanising ICU Intubation Microbiology Monitoring Neurology Nutrition Obesity Organ Donation Oxygen Paediatrics Pain Perioperative Care Pneumonia Pulmonary Embolism Rehabilitation Renal RSI Sedation Sepsis Shock Steroids Stroke Surgery Temperature Control Tracheostomy Transfusion Trauma Ultrasound Vasopressors Ventilation In patients with in-hospital cardiac arrest, does Shenfu (a traditional Chinese medicine), improve 28 day mortality? doi:10.1136/thoraxjnl-2016-209858 Clinical Question Does an increased intensity of ICU based physical rehabilitation therapy improve improve long-term physical quality of life compared with a standard intensity of physical rehabilitation?Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): a multicentre, parallel-group, randomised controlled trial Wright. Background Physical and psychological recovery after a period of critical […] In adults with out of hospital cardiac arrest (OOHCA) due to a presumed cardiac cause, who are post ‘return of spontaneous circulation’ (ROSC), does cooling to 33°C for 48 hours, compared with 24 hours, improve improved neurological outcomes at 6 months?
There is published evidence suggesting that sedatives and analgesics, intended for increased patient comfort, may contribute to the development of delirium.11–14 However, there are no prospective ICU studies addressing the temporal relation between time of administration of sedatives/analgesics and development of delirium, , it is difficult to ascertain from the literature whether sedatives and analgesics were administered to treat the delirium or whether the exposure to these agents resulted in delirium.Introduction: Delirium in the intensive care unit (ICU) is associated with increased mortality and poor outcomes.The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) is a validated screening tool used to assess delirium.Limited data exist regarding optimal pharmacologic and non-pharmacologic prevention and management of delirium.This study sought to evaluate the impact of a pharmacist-led intervention on delirium assessment and management.